Publications

  • Guo F*, Sun Y*, Wang X, Wang H, Wang J, Gong T, Chen X, Zhang P, Su L, Fu G, Su J, Yang S, Lai R, Jiang C#, Liang P#. Patient-specific and gene-corrected induced pluripotent stem cell-derived cardiomyocytes elucidate single-cell phenotype of short QT syndrome. Circulation Research 2018 (In press) (*Co-first author) (#Co-corresponding author)
  • Tang L, Fang Yao F, Wang H, Wang X, Shen J, Dai B, Wu H, Zhou D, Guo F, Wang J, Li T, Wang H, Gong T, Su J*, Wang L*, Liang P*. Inhibition of TRPC1 prevents cardiac hypertrophy via NF-κB signaling pathway in human pluripotent stem cell-derived cardiomyocytes. JMCC 2018; 126: 143-154 (#Co-corresponding author)
  • Shen J, Wang X, Zhou D, Li T, Tang L, Gong T, Su J, Liang P. Modeling cadmium-induced cardiotoxicity using human pluripotent stem cell-derived cardiomyocytes. JCMM 2018; 22 (9): 4221-4235
  • Luo L, Li B, Wang S, Wu F, Wang X, Liang P, Ombati R, Chen J, Lu X, Cui J, Lu Q, Zhang L, Zhou M, Tian C, Yang S, Lai R. Centipedes subdue giant prey by blocking KCNQ channels. PNAS 2018; 115 (7): 1646-1651
  • Tang L*, Su J*, Liang P. Modeling cadmium-induced endothelial toxicity using human pluripotent stem cell-derived endothelial cells. Scientific Reports 2017; 7 (1): 14811 (*Co-first author)
  • Li B*, Yang H*, Wang X*, Zhang Y, Sheng W, Cai H, Xin H, Liang Q, Zhou P, Lu C, Qian R, Chen S, Yang P, Zhang J, Shou W, Huang G#, Liang P#, Sun N#. Engineering human ventricular heart muscles based on a highly efficient system for purification of human pluripotent stem cell-derived ventricular cardiomyocytes. Stem Cell Research & Therapy2017; 8:202 (*Co-first author) (#Co-corresponding author)
  • Liang P*#, Sallam K*, Wu H*, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, Churco J, Hu S, Sharma A, Lam CK, Scheinmman MM, Bers DM, Wu JC#. JACC 2016; 68 (19): 2086-2096 (*Co-first author) (#Co-corresponding author)
  • Wu S, Zhu Y, Liu H, Tang L, Du R, Shen Y, Feng J, Zhang K, Xu C, Zhang S, Chen Y, Song F, Zhu Y, Gu W, Liang P, Carrio I, Zhang H, Tian M. J Nucl Med 2016; 57 (12): 2012-2015
  • Ebert AD, Kodo K, Liang P, Wu H, Huber BC, Riegler J, Churko J, Lee J, Almeida PE, Lan F, Diecke S, Burridge PW, Gold JD, Mochly-Rosen D, Wu JC. Characterization of the molecular mechanisms underlying increased ischemic damage in the aldehyde dehydrogenase 2 genetic polymorphism using a human induced pluripotent stem cell model system. Sci Transl Med 2014; 6 (255): 255ra130
  • Sharma A, Marceau CD, Hamaguchi R, Burridge P, Rajarajan K, Churko J, Wu H, Sallam K, Matsa E, Sturzu A, Che Y, Ebert A, Diecke S, Liang P, Red-Horse K, Carette JE, Wu SM, Wu JC. Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. Circ Res 2014; 115 (6): 556-66
  • Wang Y*, Liang P*, Lan F*, Wu H*, Lisowski L, Gu M, Hu S, Kay M, Urnov F, Shinnawi R, Gold J, Gepstein L, Wu JC. Genome editing of isogenic human induced pluripotent stem cells recapitulates Long QT phenotype for drug testing. JACC 2014; 64 (5): 451-9 (*Co-first author)
  • Sanchez VF, Lee AS, Hu S, Abilez OJ, Liang P, Lan F, Huber B, Ong S, Hong W, Huang M, Wu JC. Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells. JACC 2014; 64 (5): 436-48
  • Liang P, Du J. Human induced pluripotent stem cell for modeling cardiovascular diseases. Regenerative Medicine Research 2014; 2:4
  • Navarrete EG*, Liang P*, Lan F*, Sanchez-Freire V, Simmons CS, Gong T, Sharma A, Burridge PW, Patlolla B, Lee AS, Beygui RE, Bers DM, Wu JC. Screening drug-induced arrhythmia events using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. Circulation 2013; 128: S3-S13 (*Co-first author)
  • Tang Y, Liang P, Zhou J, Lu Y, Lei L, Bian X, and Wang K. Auxiliary KChIP4a suppresses A-type K+ current through ER retention and promoting closed-state inactivation of Kv4 channels. J Biol Chem 2013; 288 (21): 14727-41
  • Liang P*, Lan F*, Lee AS*, Gong T, Sanchez VF, Wang Y, Diecke S, Sallam K, Knowles JW, Wang PJ, Nguyen PK, Bers DM, Robbins RC, Wu JC. Drug screening using a library of human induced pluripotent stem cell derived cardiomyocytes reveals disease specific patterns of cardiotoxicity. Circulation 2013; 127 (16): 1677-1691 (Editorial by Dan Roden & Charles Hong) (2013 Circulation Best Paper Award in basic science) (*Co-first author)
  • Lan F*, Lee AS*, Liang P*, Sanchez VF, Nguyen PK, Wang L, Han L, Yen M, Wang Y, Sun N, Abilez OJ, Hu S, Ebert AD, Navarrete EG, Simmons CS, Wheeler M, Pruitt B, Lewis R, Yamaguchi Y, Ashley EA, Bers DM, Robbins RC, Longaker MT, Wu JC. Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. Cell Stem Cell 2013; 12 (1): 101-13 (Faculty 1000 “Must Read” Paper) (*Co-first author)
  • Wang Y, Zhang W, Hu S, Lan F, Lee AS, Huber B, Lisowski L, Liang P, Huang M, Almeida PE, Won J, Sun N, Robbins RC, Kay MA, Urnov FD, Wu JC. Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Circ Res 2012; 111 (12): 1494-503 (Journal cover) (Editorial by G Courties & M Nahrendorf)
  • Ebert AD, Liang P, Wu JC. Induced pluripotent stem cells as a disease modeling and drug screening platform. Journal Cardiovasc Pharmacol 2012; 60 (4): 408-16
  • Liang P, Chen H, Cui Y, Wang K. Functional rescue of Kv4.3 channel tetramerization mutants by KChIP4a. Biophysical Journal 2010; 98 (12): 2867-76
  • Zhang Y*, Su P*, Liang P, Liu T, Liu X, Liu X, Zhang B, Han T, Zhu Y, Yin D, Li J, Zhou Z, Wang K, Wang Y. The DREAM protein negatively regulates the NMDA receptor through interaction with the NR1 subunit. J Neurosci 2010; 30 (22): 7575-86 (*Co-first author)
  • Liang P*, Wang H*, Chen H*, Cui Y, Gu L, Chai J, Wang K. Structural insights into KChIP4a modulation of Kv4.3 inactivation. J Biol Chem 2009; 284 (8): 4960-4967 (*Co-first author)
  • Cui Y, Liang P, Wang K. Enhanced trafficking of tetrameric Kv4.3 channels by KChIP1 clamping. Neurochem Res 2008; 33 (10): 2078-84

Last Modified: Dec 28, 2018

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